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Phospho-CDK1-T161 pAb

Catalog # Availability Size / Price Inquiry
AMR00897N-1 50ul / $395
AMR00897N-2 100ul / $495
AMR00897N-3 200ul / $595

Phospho-CDK1-T161 pAb

Brand

Leading Biology

Catalog Number

AMR00897N

Product Type

Phosphorylated Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-CDK1-T161 pAb.

Molecular Weight

Calculated MW: 27kDa/34kDa Observed MW: 34kDa

Species Reactivity

Rabbit

Immunogen

A synthetic phosphorylated peptide around T161 of human CDK1 (NP_001777.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF,IP

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms

CDK1; CDC2; CDC28A; P34CDC2; cyclin-dependent kinase 1

Images

Western blot analysis of extracts of HeLa cells, using Phospho-CDK1-T161 antibody.

Immunofluorescence analysis of MCF-7 cells using Phospho-CDK1-T161 antibody.

Specification

Quantity

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