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Phospho-FAK-Y397 pAb

Catalog # Availability Size / Price Inquiry
AMR00892N-1 50ul / $395
AMR00892N-2 100ul / $495
AMR00892N-3 200ul / $595

Phospho-FAK-Y397 pAb

Brand

Leading Biology

Catalog Number

AMR00892N

Product Type

Phosphorylated Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-FAK-Y397 pAb.

Molecular Weight

Calculated MW: 39kDa/48kDa/63kDa/99kDa/114kDa/119kDa/120kDa Observed MW: 120kDa

Species Reactivity

Rabbit

Immunogen

A synthetic phosphorylated peptide around Y397 of human FAK (NP_722560.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:1000

Product Description

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.

Synonyms

PTK2; FADK; FAK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK; focal adhesion kinase 1

Images

Western blot analysis of extracts of various cell lines, using Phospho-FAK-Y397 antibody.

Specification

Quantity

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