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Phospho-ACACA-S79 pAb

Catalog # Availability Size / Price Inquiry
AMR00890N-1 50ul / $395
AMR00890N-2 100ul / $495
AMR00890N-3 200ul / $595

Phospho-ACACA-S79 pAb

Brand

Leading Biology

Catalog Number

AMR00890N

Product Type

Phosphorylated Antibodies

Field of Research

Endocrine & Metabolism>AMPK Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-ACACA-S79 pAb.

Molecular Weight

Calculated MW: 257kDa/259kDa/265kDa/269kDa Observed MW: 266kDa

Species Reactivity

Rabbit

Immunogen

A phospho specific peptide corresponding to residues surrounding S79 of human ACACA

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.

Synonyms

ACACA; ACAC; ACACAD; ACC; ACC1; ACCA; acetyl-CoA carboxylase 1

Images

Western blot analysis of extracts from 293 cells using Phospho-ACACA-S79 antibody.

Specification

Quantity

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