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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Phosphorylated Antibodies > Phospho-GSK3B-Y216 + GSK3A-Y279 pAb

Phospho-GSK3B-Y216 + GSK3A-Y279 pAb

Catalog # Availability Size / Price Inquiry
AMR00882N-1 50ul / $395
AMR00882N-2 100ul / $495
AMR00882N-3 200ul / $595

Phospho-GSK3B-Y216 + GSK3A-Y279 pAb

Brand

Leading Biology

Catalog Number

AMR00882N

Product Type

Phosphorylated Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-GSK3B-Y216 + GSK3A-Y279 pAb.

Molecular Weight

Calculated MW: 46kDa/48kDa Observed MW: 46kDa

Species Reactivity

Rabbit

Immunogen

A synthetic phosphorylated peptide around Y216 of human GSK3B (NP_001139628).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:100 - 1:200

Product Description

The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms

GSK3B; glycogen synthase kinase-3 beta

Images

Western blot analysis of extracts of 293 cells, using Phospho-GSK3B-Y216 antibody.

Immunohistochemistry of paraffin-embedded human breast carcinoma using Phospho-GSK3B-Y216 antibody.

Immunofluorescence analysis of methanol-fixed HeLa cells using Phospho-GSK3B-Y216 antibody.

Specification

Quantity

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