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Phospho-Tau-S404 pAb

Catalog # Availability Size / Price Inquiry
AMR00862N-1 50ul / $395
AMR00862N-2 100ul / $495
AMR00862N-3 200ul / $595

Phospho-Tau-S404 pAb

Brand

Leading Biology

Catalog Number

AMR00862N

Product Type

Phosphorylated Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-Tau-S404 pAb.

Molecular Weight

Calculated MW: 32-45kDa/78- 80kDa Observed MW: 65kDa

Species Reactivity

Rabbit

Immunogen

A phospho specific peptide corresponding to residues surrounding S404 of human Tau

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:100 - 1:200

Product Description

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Synonyms

MAPT; DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; microtubule-associated protein tau

Images

Western blot analysis of extracts of SH-SY5Y and C6 cells, using Phospho-Tau-S404 antibody.

Immunohistochemistry of paraffin-embedded rat hippocampal region tissue from a model with Alzheimer, using Phospho-Tau-S404 antibody.

Immunofluorescence analysis of methanol-fixed HeLa cells using Phospho-Tau-S404 antibody.

Specification

Quantity

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