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Phospho-mTOR-S2448 pAb

Catalog # Availability Size / Price Inquiry
AMR00842N-1 50ul / $395
AMR00842N-2 100ul / $495
AMR00842N-3 200ul / $595

Phospho-mTOR-S2448 pAb

Brand

Leading Biology

Catalog Number

AMR00842N

Product Type

Phosphorylated Antibodies

Field of Research

Endocrine & Metabolism>AMPK Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-mTOR-S2448 pAb.

Molecular Weight

Calculated MW: 288kDa Observed MW: 289kDa

Species Reactivity

Rabbit

Immunogen

A synthetic phosphorylated peptide around S2448 of human mTOR (NP_004949.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

Synonyms

MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS; mechanistic target of rapamycin

Images

Western blot analysis of extracts of NIH/3T3 and C6 cells, using Phospho-MTOR-S2448 antibody.

Immunofluorescence analysis of HeLa cells using Phospho-MTOR-S2448 antibody.

Specification

Quantity

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