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Phospho-MYC-S62 pAb

Catalog # Availability Size / Price Inquiry
AMR00833N-1 50ul / $395
AMR00833N-2 100ul / $495
AMR00833N-3 200ul / $595

Phospho-MYC-S62 pAb

Brand

Leading Biology

Catalog Number

AMR00833N

Product Type

Phosphorylated Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-MYC-S62 pAb.

Molecular Weight

Calculated MW: 48kDa/50kDa Observed MW: Refer to Figures

Species Reactivity

Rabbit

Immunogen

A phospho specific peptide corresponding to residues surrounding S62 of human MYC

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100

Product Description

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

Synonyms

MYC; MRTL; MYCC; bHLHe39; c-Myc; myc proto-oncogene protein

Images

Immunohistochemistry of paraffin-embedded rat lung using P-MYC-S62 antibody.

Immunohistochemistry of paraffin-embedded rat testis using P-MYC-S62 antibody.

Immunohistochemistry of paraffin-embedded human lung using P-MYC-S62 antibody.

Specification

Quantity

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