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Phospho-MAX-S11 pAb

Catalog # Availability Size / Price Inquiry
AMR00824N-1 50ul / $395
AMR00824N-2 100ul / $495
AMR00824N-3 200ul / $595

Phospho-MAX-S11 pAb

Brand

Leading Biology

Catalog Number

AMR00824N

Product Type

Phosphorylated Antibodies

Field of Research

Signal Transduction>MAPK-P38 Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-MAX-S11 pAb.

Molecular Weight

Calculated MW: 9kDa/11kDa/12kDa/15kDa/17kDa/18kDa Observed MW: 21kDa

Species Reactivity

Rabbit

Immunogen

A synthetic phosphorylated peptide around S11 of human MAX (NP_002373.3).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.

Synonyms

MAX; bHLHd4; protein max

Images

Western blot analysis of extracts of Jurkat cells, using Phospho-MAX-S11 antibody.

Immunofluorescence analysis of U2OS cells using Phospho-MAX-S11 antibody.

Specification

Quantity

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