> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Phosphorylated Antibodies > Phospho-MAP3K5-S83 pAbBrand |
Leading Biology | Catalog Number |
AMR00812N |
Product Type |
Phosphorylated Antibodies | Field of Research |
Cell Biology & Developmental Biology>Apoptosis |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-MAP3K5-S83 pAb.
|
||
Molecular Weight |
Calculated MW:
69kDa/154kDa
Observed MW:
155kDa
|
||
Species Reactivity |
Rabbit
|
||
Immunogen |
A phospho specific peptide corresponding to residues surrounding S83 of human MAP3K5
|
||
Cross Reactivity |
Human
|
||
Isotype |
IgG
|
||
GeneID |
|||
UniProt ID |
|||
Purity |
Affinity purification |
||
Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
|
||
Applications |
WB
|
||
Dilution |
WB 1:500 - 1:2000
|
||
Product Description |
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.
|
||
Synonyms |
MAP3K5; ASK1; MAPKKK5; MEKK5; mitogen-activated protein kinase kinase kinase 5
|
||
Images |
|
||
Specification |
|||
Quantity |
|
||
| Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
| 1 | Leading Biology | AMR00900N | Phospho-CREB1-S133 pAb | 100ul | Phosphorylated Antibodies | Cell Biology & Developmental Biology>Apoptosis |
|
$495.00 | Add Ask | |
| 2 | Leading Biology | AMR01102N | Phospho-EGFR-Y1086 pAb | 100ul | Phosphorylated Antibodies | Cardiovascular>Angiogenesis |
|
$495.00 | Add Ask | |
| 3 | Leading Biology | AMR01066N | Phospho-FLNA-S2152 pAb | 100ul | Phosphorylated Antibodies | Cell Biology & Developmental Biology>Cytoskeleton |
|
$495.00 | Add Ask | |
| 4 | Leading Biology | AMR01229N | Phospho-PDGFRB-Y771 pAb | 100ul | Phosphorylated Antibodies | Cardiovascular>Angiogenesis |
|
$495.00 | Add Ask | |
| 5 | Leading Biology | APG03384N | Phospho-Histone H2A-S129 pAb | 100ul | Phosphorylated Antibodies |
|
$495.00 | Add Ask | ||
| 6 | Leading Biology | AMR01103N | Phospho-DPYSL2-T514 pAb | 100ul | Phosphorylated Antibodies | Neuroscience>Neurodegenerative Diseases |
|
$495.00 | Add Ask |
Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
You have 0 item in your cart
You have 0 item in your inquiry list
