> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Phosphorylated Antibodies > Phospho-EIF4EBP1-S65 pAbBrand |
Leading Biology | Catalog Number |
AMR00788N |
Product Type |
Phosphorylated Antibodies | Field of Research |
Endocrine & Metabolism>AMPK Signaling Pathway |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-EIF4EBP1-S65 pAb.
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Molecular Weight |
Calculated MW:
12kDa
Observed MW:
18kDa
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Species Reactivity |
Rabbit
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Immunogen |
A synthetic phosphorylated peptide around S65 of human EIF4EBP1 (NP_004086.1).
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Cross Reactivity |
Human,Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IP
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Dilution |
WB 1:500 - 1:2000
IP 1:50 - 1:100
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Product Description |
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
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Synonyms |
EIF4EBP1; 4E-BP1; 4EBP1; BP-1; PHAS-I; eukaryotic translation initiation factor 4E-binding protein 1
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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