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Phospho-ATF2-T71 pAb

Catalog # Availability Size / Price Inquiry
AMR00778N-1 50ul / $395
AMR00778N-2 100ul / $495
AMR00778N-3 200ul / $595

Phospho-ATF2-T71 pAb

Brand

Leading Biology

Catalog Number

AMR00778N

Product Type

Phosphorylated Antibodies

Field of Research

Immunology & Inflammation>B Cell Receptor Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-ATF2-T71 pAb.

Molecular Weight

Calculated MW: 13- 15kDa/23-24kDa/35-54kDa Observed MW: 70kDa

Species Reactivity

Rabbit

Immunogen

A synthetic phosphorylated peptide around T71 of human ATF2 (NP_001871.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:1000 IHC 1:50 - 1:100 IF 1:50 - 1:100

Product Description

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene

Synonyms

ATF2; CRE-BP1; CREB-2; CREB2; HB16; TREB7; activating transcription factor 2

Images

Western blot analysis of extracts of various cell lines, using Phospho-ATF2-T71 antibody.

Immunofluorescence analysis of MCF-7 cells using Phospho-ATF2-T71 antibody.

Specification

Quantity

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