• Account
  • Account
    Inquiries
    0

    Inquired items

    0 items total Subtotal:$ 0
  • 会员中心
    Cart

    Added items

    0items total Subtotal:$ 0

All Departments

Phospho-ATM-S1981 pAb

Catalog # Availability Size / Price Inquiry
AMR00767N-1 50ul / $395
AMR00767N-2 100ul / $495
AMR00767N-3 200ul / $595

Phospho-ATM-S1981 pAb

Brand

Leading Biology

Catalog Number

AMR00767N

Product Type

Phosphorylated Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-ATM-S1981 pAb.

Molecular Weight

Calculated MW: 350kDa Observed MW: 350kDa

Species Reactivity

Rabbit

Immunogen

A synthetic phosphorylated peptide around S1981 of human ATM (NP_000042.3).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.

Synonyms

ATM; AT1; ATA; ATC; ATD; ATDC; ATE; TEL1; TELO1; serine-protein kinase ATM

Images

Western blot analysis of extracts of 293T cells, using Phospho-ATM-S1981 antibody.

Immunofluorescence analysis of MCF-7 cells using Phospho-ATM-S1981 antibody.

Immunofluorescence analysis of U2OS cells using Phospho-ATM-S1981 antibody.

Specification

Quantity

Related Products

Select Brand Catalog No. Product Name Pack Size Type Field of Research Specification Quantity Price(USD)
1 Leading Biology AMR00900N Phospho-CREB1-S133 pAb 100ul Phosphorylated Antibodies Cell Biology & Developmental Biology>Apoptosis
$495.00 Add Ask
2 Leading Biology AMR01102N Phospho-EGFR-Y1086 pAb 100ul Phosphorylated Antibodies Cardiovascular>Angiogenesis
$495.00 Add Ask
3 Leading Biology AMR01066N Phospho-FLNA-S2152 pAb 100ul Phosphorylated Antibodies Cell Biology & Developmental Biology>Cytoskeleton
$495.00 Add Ask
4 Leading Biology AMR01229N Phospho-PDGFRB-Y771 pAb 100ul Phosphorylated Antibodies Cardiovascular>Angiogenesis
$495.00 Add Ask
5 Leading Biology APG03384N Phospho-Histone H2A-S129 pAb 100ul Phosphorylated Antibodies
$495.00 Add Ask
6 Leading Biology AMR01067N Phospho-PFKFB2-S483 pAb 100ul Phosphorylated Antibodies Endocrine & Metabolism>Carbohydrate metabolism
$495.00 Add Ask

This item has successfully been added to your cart!

You have 0 item in your cart

Your inquiry has successfully been added to your list!

You have 0 item in your inquiry list