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Phospho-TP53-S15 pAb

Catalog # Availability Size / Price Inquiry
AMR01217N-1 50ul / $395
AMR01217N-2 100ul / $495
AMR01217N-3 200ul / $595

Phospho-TP53-S15 pAb

Brand

Leading Biology

Catalog Number

AMR01217N

Product Type

Phosphorylated Antibodies

Field of Research

Endocrine & Metabolism>AMPK Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-TP53-S15 pAb.

Molecular Weight

Calculated MW: 43kDa Observed MW: Refer to figures

Species Reactivity

Rabbit

Immunogen

A phospho specific peptide corresponding to residues surrounding S15 of human TP53.

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).

Synonyms

P53; BCC7; LFS1; BMFS5; TRP53

Images

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Specification

Quantity

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