> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Phosphorylated Antibodies > Phospho-Histone H3-S10 pAbBrand |
Leading Biology | Catalog Number |
AMR01122N |
Product Type |
Phosphorylated Antibodies | Field of Research |
Epigenetics & Nuclear Signaling>Epigenetic Modifications |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-Histone H3-S10 pAb.
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Molecular Weight |
Calculated MW:
15kDa
Observed MW:
17kDa
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Species Reactivity |
Rabbit
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Immunogen |
A synthetic phosphorylated peptide around S10 of human Histone H3 (NP_003484.1).
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Cross Reactivity |
Human
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB
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Dilution |
WB 1:500 - 1:2000
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Product Description |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
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Synonyms |
HIST3H3; H3.4; H3/g; H3FT; H3t; histone H3.1t
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Images |
Western blot analysis of extracts of HeLa cells, using Phospho-Histone H3-S10 antibody. |
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Specification |
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Quantity |
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