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Phospho-CRKL-Y207 pAb

Catalog # Availability Size / Price Inquiry
AMR01106N-1 50ul / $395
AMR01106N-2 100ul / $495
AMR01106N-3 200ul / $595

Phospho-CRKL-Y207 pAb

Brand

Leading Biology

Catalog Number

AMR01106N

Product Type

Phosphorylated Antibodies

Field of Research

Signal Transduction>Kinase

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-CRKL-Y207 pAb.

Molecular Weight

Calculated MW: 33kDa Observed MW: 38kDa

Species Reactivity

Rabbit

Immunogen

A synthetic phosphorylated peptide around Y207 of human CRKL (NP_005198.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100

Product Description

This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.

Synonyms

CRKL; crk-like protein

Images

Western blot analysis of extracts of K-562 cells, using Phospho-CRKL-Y207 antibody.

Immunohistochemistry of paraffin-embedded rat brain using Phospho-CRKL-Y207 antibody.

Specification

Quantity

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