> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > Syntaxin 1A AntibodyBrand |
Leading Biology | Catalog Number |
APR10367G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Syntaxin 1A antibody.
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Molecular Weight |
36 KDa
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Host |
Mouse
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Species Reactivity |
Human, Hamster, Pig, Rat
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Target |
Synaptic immunoprecipitate (crude) from human brain.
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Clone |
SP8
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Isotype |
IgG1
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GeneID |
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UniProt ID |
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Summary |
Syntaxins are a family of proteinsinvolved in the docking of synapticvesicles with the plasma membrane. Syntaxin, along with synaptobrevin and SNAP-25, formsthe SNARE complex which mediates synaptic vesicle fusion and exocytosis. Binding ofMunc18-1 to the N-terminus of syntaxin 1 hasbeen demonstrated to be essential for exocyticmembrane fusion (Khvotchev et al., 2007). Decreased levels of phosphorylated syntaxin 1 inthe prefrontal cortex have recently been correlated with schizophrenia (Castillo et al., 2010).
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Form |
Protein G purified culture supernatant. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB
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Dilution |
WB~~ 1:1000
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Synonyms |
Syntaxin-1A, Neuron-specific antigen HPC-1, STX1A, STX1
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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