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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > Calcitonin Gene Related Peptide (CGRP) Antibody

Calcitonin Gene Related Peptide (CGRP) Antibody

Catalog # Availability Size / Price Inquiry
APR11543G 100 μl / $545

Calcitonin Gene Related Peptide (CGRP) Antibody

Brand

Leading Biology

Catalog Number

APR11543G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Calcitonin Gene Related Peptide (CGRP) antibody.

Molecular Weight

13948 Da

Host

Mouse

Species Reactivity

Human, Rat

Target

Purified rat alpha-CGRP.

Clone

4901

Isotype

IgG2a

GeneID

UniProt ID

Summary

Calcitonin Gene Related Peptide [CGRP] is a 37 amino acid peptide and is the most potent endogenous vasodilator currently known (Brain et al.,1985). CGRP is primarily produced in nervous tissue, however, its receptors are expressed throughout the body. CGRP is also strongly implicated in the vasodilatory effect of endogenous cannabinoid anandamide in the brain. This effect was found to be antagonized by capsazepine. CGRP is also currently a major target of research in regards to factors effecting the onset of migraine headaches (Edvinsson L., 2003). CGRP antibodies have been used successfully in immunoneutralization (Wong et al., 1993)

Form

Protein G purified

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

ICC

Dilution

ICC~~1:50-1:100

Synonyms

Calcitonin gene-related peptide 1, Alpha-type CGRP, Calcitonin gene-related peptide I, CGRP-I, Calca, Calc

Images

Immunostaining of CGRP (red) in cryopreserved DRG neurons grown on coverslips. 40xmag. Green staining is PGP9.5. Yellow staining is the colocalization of CGRP and PGP9.5. Cells were obtained and photo was provided courtesy of QBMCellScience.

Specification

Quantity

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