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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > Norepinephrine Transporter Antibody

Norepinephrine Transporter Antibody

Catalog # Availability Size / Price Inquiry
AMM06749G 100 μl / $545

Norepinephrine Transporter Antibody

Brand

Leading Biology

Catalog Number

AMM06749G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Norepinephrine Transporter antibody.

Molecular Weight

55 KDa

Host

Mouse

Species Reactivity

Mouse, Rat

Target

Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH.

Clone

NET-05

Isotype

IgG2b

GeneID

UniProt ID

Summary

Norepinephrine Transporter [NET] (or noradrenaline transporter (NAT)) is a monoamine transporter that transports the neurotransmitter noradrenaline from the synapse back to its vesicles for storage until later use. It also appears to transport the neurotransmitter dopamine in the same way, but to a lesser degree. Studies have shown a decrease in NET levels in the locus coeruleus in patients diagnosed with major depression (Klimek et al., 1997). Cocaine, amphetamines and many therapeutic antidepressants, such as the SNRIs (Serotonin-norepinephrine reuptake inhibitors) and the tricyclic antidepressants (TCAs) act to raise noradrenaline. Furthermore, deficits in the NET gene have been associated with ADHD (Kim et al., 2006).

Form

Protein G purified culture supernatant.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Dilution

WB~~ 1:2000

Synonyms

Sodium-dependent noradrenaline transporter, Norepinephrine transporter, NET, Solute carrier family 6 member 2, Slc6a2

Images

Western blot of rat cortex homogenate showing specific immunolabelingof the ~ 55k norepinephrine transporter protein.

Specification

Quantity

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