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CDX2 Antibody

Catalog # Availability Size / Price Inquiry
AMM05748G 100 μl / $545

CDX2 Antibody

Brand

Leading Biology

Catalog Number

AMM05748G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CDX2 antibody.

Molecular Weight

33.5kDa

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Mouse

Species Reactivity

Human

Clone

2F12A6

Isotype

IgG1

Symbol

CDX3

GeneID

UniProt ID

Function

Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.

Summary

The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene. ;

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

E~~1/10000 WB~~1/500 - 1/2000

Synonyms

Homeobox protein CDX-2, CDX-3, Caudal-type homeobox protein 2, CDX2, CDX3

Images

Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Figure 1: Western blot analysis using CDX2 mAb against human CDX2 (AA: 176-303) recombinant protein. (Expected MW is 40.1 kDa)

Figure 2: Western blot analysis using CDX2 mAb against HEK293 (1) and CDX2 (AA: 176-303)-hIgGFc transfected HEK293 (2) cell lysate.

Specification

Quantity

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