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SOX10 Antibody

Catalog # Availability Size / Price Inquiry
APR10208G 100 μl / $545

SOX10 Antibody

Brand

Leading Biology

Catalog Number

APR10208G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SOX10 antibody.

Molecular Weight

49.9kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus.

Host

Mouse

Species Reactivity

Human

Clone

2E7B5

Isotype

IgG1

GeneID

UniProt ID

Function

Transcription factor that seems to function synergistically with the POU domain protein TST-1/OCT6/SCIP. Could confer cell specificity to the function of other transcription factors in developing and mature glia (By similarity).

Summary

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. ;

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

E~~1/10000 WB~~1/500 - 1/2000 FC~~1/200 - 1/400

Synonyms

Transcription factor SOX-10, SOX10

Images

Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Figure 1: Western blot analysis using SOX10 mAb against human SOX10 recombinant protein. (Expected MW is 31.7 kDa)

Figure 2: Western blot analysis using SOX10 mAb against HEK293 (1) and SOX10 (AA: 147-252)-hIgGFc transfected HEK293 (2) cell lysate.

Specification

Quantity

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