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SRA Antibody

Catalog # Availability Size / Price Inquiry
AMM07964G 100 μl / $495

SRA Antibody

Brand

Leading Biology

Catalog Number

AMM07964G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SRA antibody.

Molecular Weight

25673 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm

Host

Mouse

Species Reactivity

Human

Clone

7H1G1

Isotype

IgG1

GeneID

UniProt ID

Function

Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand- dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, E

Dilution

WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000

Synonyms

Steroid receptor RNA activator 1, Steroid receptor RNA activator protein, SRAP, SRA1 (HGNC:11281)

Images

Figure 1: Western blot analysis using SRA mouse mAb against truncated SRA recombinant protein (1) and human ovary cancer tissue lysate (2).

Figure 2: Immunohistochemical analysis of paraffin-embedded human bladder carcinoma (left) and breast carcinoma (right), showing nuclear and cytoplasmic localization using SRA mouse mAb with DAB staining.

Specification

Quantity

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