> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > CREB3 Antibody (monoclonal) (M01)Brand |
Leading Biology | Catalog Number |
AMM05357G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CREB3 antibody (monoclonal) (M01).
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Molecular Weight |
43917 Da
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Host |
mouse
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Species Reactivity |
Human
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Target |
CREB3 (NP_006359, 273 a.a. ~ 371 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Clone |
3H5
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Isotype |
IgG2a Kappa
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GeneID |
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UniProt ID |
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Summary |
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.
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Form |
Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC, E
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Dilution |
WB~~1:500~1000
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Synonyms |
Cyclic AMP-responsive element-binding protein 3, CREB-3, cAMP-responsive element-binding protein 3, Leucine zipper protein, Luman, Transcription factor LZIP-alpha, Processed cyclic AMP-responsive element-binding protein 3, N-terminal Luman, Transcriptionally active form, CREB3, LZIP
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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