> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > CAT Antibody (Center) (Ascites)Brand |
Leading Biology | Catalog Number |
APR07085G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CAT antibody (Center) (Ascites).
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Molecular Weight |
59756 Da
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Cellular Localization |
Antigen Cellular Localization:
Peroxisome.
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Host |
Mouse
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Species Reactivity |
Human, Mouse
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Immunogen |
152-180 aa
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Target |
This CAT antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the Central region of human CAT.
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Clone |
626CT4.3.8
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Isotype |
IgG2a
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GeneID |
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UniProt ID |
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Function |
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
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Summary |
This gene encodes catalase, a key antioxidant enzyme inthe bodies defense against oxidative stress. Catalase is a hemeenzyme that is present in the peroxisome of nearly all aerobiccells. Catalase converts the reactive oxygen species hydrogenperoxide to water and oxygen and thereby mitigates the toxiceffects of hydrogen peroxide. Oxidative stress is hypothesized toplay a role in the development of many chronic or late-onsetdiseases such as diabetes, asthma, Alzheimer's disease, systemiclupus erythematosus, rheumatoid arthritis, and cancers.Polymorphisms in this gene have been associated with decreases incatalase activity but, to date, acatalasemia is the only diseaseknown to be caused by this gene.
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Form |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:100~1600
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Synonyms |
Catalase, CAT
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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