> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > GJC2 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
AMM05917G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GJC2 antibody (N-term).
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Molecular Weight |
47002 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction
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Host |
Mouse
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Species Reactivity |
Human
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Immunogen |
32-61 aa
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Target |
This GJC2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human GJC2.
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Clone |
391CT6.4.3
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Isotype |
IgM
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Symbol |
GJA12
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GeneID |
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UniProt ID |
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Function |
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a role in myelination in central and peripheral nervous systems.
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Summary |
GJC2 is a gap junction protein. Gap junctionproteins are members of a large family of homologous connexins andcomprise 4 transmembrane, 2 extracellular, and 3 cytoplasmicdomains. This gene plays a key role in central myelination and isinvolved in peripheral myelination in humans. Defects in this geneare the cause of autosomal recessive Pelizaeus-Merzbacher-likedisease-1.
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Form |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:100~500
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Synonyms |
Gap junction gamma-2 protein, Connexin-466, Cx466, Connexin-47, Cx47, Gap junction alpha-12 protein, GJC2, GJA12
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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