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GJC2 Antibody (N-term)(Ascites)

Catalog # Availability Size / Price Inquiry
AMM05918G 0.1 ml / $495

GJC2 Antibody (N-term)(Ascites)

Brand

Leading Biology

Catalog Number

AMM05918G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GJC2 antibody (N-term)(Ascites).

Molecular Weight

47002 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein. Cell junction, gap junction

Host

Mouse

Species Reactivity

Human

Immunogen

53-78 aa

Target

This GJC2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 53-78 amino acids from the N-terminal region of human GJC2.

Clone

391CT6.4.3

Isotype

IgM

Symbol

GJA12

GeneID

UniProt ID

Function

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a role in myelination in central and peripheral nervous systems.

Summary

GJC2 is a gap junction protein. Gap junctionproteins are members of a large family of homologous connexins andcomprise 4 transmembrane, 2 extracellular, and 3 cytoplasmicdomains. This gene plays a key role in central myelination and isinvolved in peripheral myelination in humans. Defects in this geneare the cause of autosomal recessive Pelizaeus-Merzbacher-likedisease-1.

Form

Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:100~8000

Synonyms

Gap junction gamma-2 protein, Connexin-466, Cx466, Connexin-47, Cx47, Gap junction alpha-12 protein, GJC2, GJA12

Images

GJC2 Antibody (N-term) (Cat. AMM05918G) western blot analysis in A549 cell line lysates (35μg/lane).This demonstrates the GJC2 antibody detected the GJC2 protein (arrow).

Specification

Quantity

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