> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > THBS1 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR10934G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality THBS1 antibody (Center).
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Molecular Weight |
129383 Da
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Cellular Localization |
Antigen Cellular Localization:
Endoplasmic reticulum. Sarcoplasmic reticulum
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Host |
Mouse
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Species Reactivity |
Human
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Immunogen |
763-789 aa
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Target |
This THBS1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 763-789 amino acids from the Central region of human THBS1.
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Clone |
518CT18.12.8
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Isotype |
IgM
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Symbol |
TSP, TSP1
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GeneID |
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UniProt ID |
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Function |
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors (By similarity).
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Summary |
The protein encoded by this gene is a subunit of adisulfide-linked homotrimeric protein. This protein is an adhesiveglycoprotein that mediates cell-to-cell and cell-to-matrixinteractions. This protein can bind to fibrinogen, fibronectin,laminin, type V collagen and integrins alpha-V/beta-1. This proteinhas been shown to play roles in platelet aggregation, angiogenesis,and tumorigenesis.
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Form |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:100~250
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Synonyms |
Thrombospondin-1, THBS1, TSP, TSP1
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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