> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > Peroxiredoxin-6 AntibodyBrand |
Leading Biology | Catalog Number |
APR09050G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Peroxiredoxin-6 antibody.
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Molecular Weight |
25035 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Lysosome. Cytoplasmic vesicle. Note=Also found in lung secretory organelles.
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
A synthetic peptide corresponding to residues in human Peroxiredoxin 6 was used as an immunogen.
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Clone |
EPR3755
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Symbol |
AOP2, KIAA0106
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GeneID |
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UniProt ID |
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Function |
Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.
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Summary |
Peroxiredoxin 6, a member of the thiol-specific antioxidant protein family (1), is an enzyme that detoxifies hydrogen peroxide and various organic peroxides (2). It is a cytosolic peroxidase that has been demonstrated to protect various tissues, such as skin, lung, and cardiac muscle, against acute oxidative insults (3). Peroxiredoxin 6 has two distinct active sites, and is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides (1). Peroxiredoxin 6 has been hypothesized to also protect the liver from oxidative stress generated during the process of chronic ethanol ingestion (3), and may play a role in the regulation of phospholipid turnover (1).
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Form |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC, IF
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Dilution |
WB~~1:1000~10000
IHC~~1:100~250
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Synonyms |
Peroxiredoxin-6, 1-Cys peroxiredoxin, 1-Cys PRX, 24 kDa protein, Acidic calcium-independent phospholipase A2, aiPLA2, 311-, Antioxidant protein 2, Liver 2D page spot 40, Non-selenium glutathione peroxidase, NSGPx, Red blood cells page spot 12, PRDX6, AOP2, KIAA0106
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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