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Neurofilament M Antibody

Catalog # Availability Size / Price Inquiry
AMM06639G 100 μl / $545

Neurofilament M Antibody

Brand

Leading Biology

Catalog Number

AMM06639G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Neurofilament M antibody.

Molecular Weight

102472 Da

Host

Rabbit

Species Reactivity

Human

Target

A synthetic peptide corresponding to residues in human Neurofilament M was used as an immunogen.

Clone

EP2460

Symbol

NEF3, NFM

GeneID

UniProt ID

Function

Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber.

Summary

Neuofilaments (NF) are members of the intermediate filament protein family also known as 10nm filaments. These neuron-specific filaments are the major constituents of the axonal cytoskeleton (1). NFs are composed of three major proteins; NF-H, NF-M and NF-L and the ratio of each protein changes during neuronal development. NF-H is the heavy molecular weight protein (200 kDa), NF-M the medium (160 kDa) and NF-L the light protein (68kDa) (2).

Form

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, IF

Dilution

WB~~1:1000~10000 IHC~~1:250~500

Synonyms

Neurofilament medium polypeptide, NF-M, 160 kDa neurofilament protein, Neurofilament 3, Neurofilament triplet M protein, NEFM, NEF3, NFM

Images

Western blot analysis on (A) 293T and (B) SH-SY5Y cell lysates using anti-Neurofilament M RabMAb (Cat. AMM06639G).

Immunohistochemical analysis of paraffin-embedded human normal brain tissue using anti-Neurofilament M RabMAb (Cat. AMM06639G).

Immunohistochemical analysis of paraffin-embedded human glioma using anti-Neurofilament M RabMAb (Cat. AMM06639G).

Specification

Quantity

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