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LDH-B Antibody (Heart Subunit)

Catalog # Availability Size / Price Inquiry
APR08170G 100 μl / $545

LDH-B Antibody (Heart Subunit)

Brand

Leading Biology

Catalog Number

APR08170G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LDH-B antibody (Heart Subunit).

Molecular Weight

36638 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

A synthetic peptide corresponding to residues in human LDH-B was used as immunogen.

Clone

EP1566Y

GeneID

UniProt ID

Summary

Lactate dehydrogenase (LDH) is an ubiquitous enzyme commonly found in wide variety of organisms, including plants and microbes. LDH is involved in the interconversion of the pyruvate and NADH to lactate and NAD+. It is also called Hydroxybutyrate Dehydrogenase (HBD), because it can catalyze the oxidation of hydroxybutyrate (1). In mammals, three types of LDH subunits (35 kDa) are encoded by the genes Ldh-A, Ldh-B, and Ldh-C. All LDH subunits can combine to form various terameric isoenzymes (140 kDa). Lactate dehydrogenase B (LDH-B, heart subunit, LDH-H) is involved in the conversion of L-lactate and NAD to pryruvate and NADH and it is predominantly localized in the heart tissue. Similar to other LDH subunit, LDH-B is considered to be an important marker for germ cell tumor (2).

Form

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC, WB

Dilution

IHC~~1:50~1:100 WB~~1:1000~10000

Synonyms

L-lactate dehydrogenase B chain, LDH-B, LDH heart subunit, LDH-H, Renal carcinoma antigen NY-REN-46, LDHB

Images

B.Immunohistochemical analysis of paraffin-embedded human liver carcinoma using anti-LDH-B RabMAb (Cat. APR08170G).

A.Western blot analysis on HeLa cell lysate using anti-LDH-B RabMAb (Cat. APR08170G).

Specification

Quantity

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