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Park7 (DJ-1) Antibody

Catalog # Availability Size / Price Inquiry
AMM02594G 100 μl / $545

Park7 (DJ-1) Antibody

Brand

Leading Biology

Catalog Number

AMM02594G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Park7 (DJ-1) Antibody.

Molecular Weight

21 KDa

Host

Mouse

Species Reactivity

Bovine, Human, Mouse, Rat

Target

Full length recombinant human Park7 expressed in and purified from E. coli.

Clone

4H4

Isotype

IgG1

GeneID

UniProt ID

Summary

Park7, also known as DJ-1, is a member of the peptidase C56 family of proteins and is thought to function as a molecular chaperone. Mutations in park7 have been associated with autosomal recessive, early onset Parkinson’s disease (Bonifati et al., 2003). Recently, park7 has been shown to inhibit microtubule associated protein 1B aggregation thus leading to neuronal apoptosis (Wang et al., 2011).

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, IF

Dilution

FC~~1:500 WB~~ 1:2000 IF~~ 1:500

Images

Flow cytometric analysis of Hela cells using Park7 (DJ-1) Antibody(green, AMM02594G) compared to an isotype control of mouse IgG1(blue). AMM02594G was diluted at 1:500 dilution. An Alexa Fluor? 488 goat anti-mouse lgG at 1:400 dilution was used as the secondary antibody.

Western blot of rat kidney lysate showing specific immunolabeling of the ~21k park7 protein.

Immunofluorescence of HeLa cells stained with anti-park7 (green) showing strong cytoplasmic staining and anti-vimentin antibody (red).

Specification

Quantity

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