• Account
  • Account
    Inquiries
    0

    Inquired items

    0 items total Subtotal:$ 0
  • 会员中心
    Cart

    Added items

    0items total Subtotal:$ 0

All Departments

DDR2 Antibody

Catalog # Availability Size / Price Inquiry
AMM02646G 100 μl / $545

DDR2 Antibody

Brand

Leading Biology

Catalog Number

AMM02646G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DDR2 Antibody.

Molecular Weight

96736 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single- pass type I membrane protein

Host

Mouse

Species Reactivity

Human

Clone

3B11E4

Isotype

IgG2a

Symbol

NTRKR3, TKT, TYRO10

GeneID

UniProt ID

Function

Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, ICC, E

Dilution

WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000 IF~~1/200 - 1/1000

Images

Figure 1: Western blot analysis using DDR2 mouse mAb against truncated DDR2 recombinant protein.

Figure 2: Immunohistochemical analysis of paraffin-embedded human skeletal musle tissues using DDR2 mouse mAb.

Figure 3: Confocal immunofluorescence analysis of A549 cells using DDR2 mouse mAb (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.

Specification

Quantity

Related Products

Select Brand Catalog No. Product Name Pack Size Type Field of Research Specification Quantity Price(USD)
1 Leading Biology APG02467G CCK4 / PTK7 Antibody (clone 4F9) 50 μl Monoclonal Antibodies
$495.00 Add Ask
2 Leading Biology AMM04683G GALT Antibody (clone 4C11) 50 μg Monoclonal Antibodies
$545.00 Add Ask
3 Leading Biology AMM01402G Vimentin (Mesenchymal Cell Marker) Antibody - With BSA and Azide 50 ug Monoclonal Antibodies
$395.00 Add Ask
4 Leading Biology APR08280G LTA4H / LTA4 Antibody (clone 9G8) 50 μl Monoclonal Antibodies
$495.00 Add Ask
5 Leading Biology AMM00172G CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody - With BSA and Azide 50 ug Monoclonal Antibodies
$395.00 Add Ask
6 Leading Biology AMM05750G CEBPA Antibody 100 μl Monoclonal Antibodies
$545.00 Add Ask

This item has successfully been added to your cart!

You have 0 item in your cart

Your inquiry has successfully been added to your list!

You have 0 item in your inquiry list