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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > PAX7 (Rhabdomyosarcoma Marker) Antibody

PAX7 (Rhabdomyosarcoma Marker) Antibody

Catalog # Availability Size / Price Inquiry
AMM01162G 7 ml / $495

PAX7 (Rhabdomyosarcoma Marker) Antibody

Brand

Leading Biology

Catalog Number

AMM01162G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PAX7 (Rhabdomyosarcoma Marker) Antibody.

Molecular Weight

57kDa

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Mouse

Species Reactivity

Human

Clone

PAX7/1187

Isotype

Mouse / IgG1, kappa

Symbol

HUP1

GeneID

UniProt ID

Function

Transcription factor playing a role in myogenesis through regulation of muscle precursor cells proliferation.

Summary

The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC

Images

Formalin-fixed, paraffin-embedded human Rhabdomyosarcoma stained with PAX7 Monoclonal Antibody (PAX7/1187).

Formalin-fixed, paraffin-embedded human Testicular Carcinoma stained with PAX7 Monoclonal Antibody (PAX7/1187).

Specification

Quantity

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