> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > MyoD1 Antibody (N-term) (Ascites)Brand |
Leading Biology | Catalog Number |
AMM02438G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MyoD1 Antibody (N-term) (Ascites).
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Molecular Weight |
34501 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus.
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Host |
Mouse
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Species Reactivity |
Human
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Immunogen |
105-134 aa
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Target |
This MyoD1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 105-134 amino acids from the N-terminal region of human MyoD1.
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Clone |
598CT21.2.4
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Isotype |
IgM
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Symbol |
BHLHC1, MYF3, MYOD
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GeneID |
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UniProt ID |
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Function |
Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity).
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Summary |
This gene encodes a nuclear protein that belongs to thebasic helix-loop-helix family of transcription factors and themyogenic factors subfamily. It regulates muscle celldifferentiation by inducing cell cycle arrest, a prerequisite formyogenic initiation. The protein is also involved in muscleregeneration. It activates its own transcription which maystabilize commitment to myogenesis.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:100~2000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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