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IGF2 Antibody

Catalog # Availability Size / Price Inquiry
AMM02414G 100 μl / $495

IGF2 Antibody

Brand

Leading Biology

Catalog Number

AMM02414G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IGF2 Antibody.

Molecular Weight

20140 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Mouse

Species Reactivity

Human

Immunogen

39-68 aa

Target

This IGF2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from human IGF2.

Clone

519CT14.3.6

Isotype

IgM

GeneID

UniProt ID

Function

The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development.

Summary

This gene encodes a member of the insulin family ofpolypeptide growth factors, which are involved in development andgrowth. It is an imprinted gene, expressed only from the paternalallele, and epigenetic changes at this locus are associated withWilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, andSilver-Russell syndrome. A read-through INS-IGF2 gene exists, whose5' region overlaps the INS gene and the 3' region overlaps thisgene. Alternatively spliced transcript variants encoding differentisoforms have been found for this gene.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:100~500

Images

IGF2 Antibody (Cat. AMM02414G) western blot analysis in A549 cell line lysates (35μg/lane).This demonstrates the IGF2 antibody detected the IGF2 protein (arrow).

Specification

Quantity

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