> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > P100 AntibodyBrand |
Leading Biology | Catalog Number |
AMM02324G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality P100 Antibody.
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Molecular Weight |
85653 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. Is released from the nucleus in apoptotic cells and is detected on apoptotic microtubules
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Host |
Mouse
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Species Reactivity |
Human, Mouse
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Target |
This monoclonal antibody is generated from mice immunized with four KLH conjugated synthetic peptides selected from human P100.
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Clone |
19AT738.292
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Isotype |
Mouse IgG1
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Symbol |
C20orf1, C20orf2, DIL2, HCA519
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GeneID |
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UniProt ID |
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Function |
Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:100~500
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Images |
Western analysis of extracts from Jurkat cells using P100 antibody. |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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