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VEGF3 Antibody

Catalog # Availability Size / Price Inquiry
AMM02323G 100 μl / $495

VEGF3 Antibody

Brand

Leading Biology

Catalog Number

AMM02323G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality VEGF3 Antibody.

Molecular Weight

46883 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Mouse

Species Reactivity

Human, Mouse

Target

This monoclonal antibody is generated from mice immunized with three KLH conjugated synthetic peptides selected from the N-terminal, central, and C-terminal regions of human VEGF3.

Clone

30AT1174.77

Isotype

Mouse IgG1

GeneID

UniProt ID

Function

Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.

Summary

The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:100~500

Images

All lanes : Anti-VEGF3 Antibody at 1:2000 dilution Lane 1: human ovary lysate Lane 2: human testis lysate Lane 3: mouse heart lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 47 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Western analysis of extracts from HDMEC cells using VEGF3 antibody.

Specification

Quantity

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