> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > Cytokeratin 8/18 Antibody - With BSA and AzideBrand |
Leading Biology | Catalog Number |
AMM00140G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Cytokeratin 8/18 Antibody - With BSA and Azide.
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Molecular Weight |
52.5kDa (CK8); 45kDa (CK18)
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Nucleus, nucleoplasm Nucleus matrix
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Host |
Mouse
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Species Reactivity |
Human
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Target |
Keratin preparation from a human carcinoma (K8.8); PMC-42 human breast carcinoma cells (DC10)
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Clone |
K8.8 + DC10
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Isotype |
IgG1, kappa + IgG1, kappa
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Symbol |
CYK8
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GeneID |
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UniProt ID |
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Function |
Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
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Summary |
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. Immunohistochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.
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Form |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC, IF, FC, IP
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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