> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > HSP27 (Heat Shock Protein 27) Antibody - With BSA and AzideBrand |
Leading Biology | Catalog Number |
AMM00112G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HSP27 (Heat Shock Protein 27) Antibody - With BSA and Azide.
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Molecular Weight |
27kDa
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles
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Host |
Mouse
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Species Reactivity |
Human, Mouse, Rat
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Target |
Partially purified hsp27 (earlier called 24K) protein from breast cancer MCF-7 cells.
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Clone |
G3.1
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Isotype |
IgG1, kappa
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Symbol |
HSP27, HSP28
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GeneID |
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UniProt ID |
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Function |
Involved in stress resistance and actin organization.
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Summary |
It recognizes a 24-27kDa estrogen-regulated protein, identified as heat shock protein 27 (hsp27). Hsp27 was recently found to be identical to the estrogen-induced “p29” and “24K” protein. About 50% of breast carcinomas are positive for hsp27 especially those that are also positive for estrogen and/or progesterone receptor. HSP27 has also been implicated in drug resistance in cancer cells.
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Form |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC, IF, FC, IP, E
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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