• Account
  • Account
    Inquiries
    0

    Inquired items

    0 items total Subtotal:$ 0
  • 会员中心
    Cart

    Added items

    0items total Subtotal:$ 0

All Departments

Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > FOXP3 (Forkhead Box Protein P3) / Scurfin Antibody - With BSA and Azide

FOXP3 (Forkhead Box Protein P3) / Scurfin Antibody - With BSA and Azide

Catalog # Availability Size / Price Inquiry
AMM00111G 50 ug / $395

FOXP3 (Forkhead Box Protein P3) / Scurfin Antibody - With BSA and Azide

Brand

Leading Biology

Catalog Number

AMM00111G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FOXP3 (Forkhead Box Protein P3) / Scurfin Antibody - With BSA and Azide.

Molecular Weight

47-55kDa

Cellular Localization

Antigen Cellular Localization: Nucleus {ECO:0000255|PROSITE- ProRule:PRU00089}

Host

Mouse

Species Reactivity

Human, Mouse, Monkey

Target

Full-length human FOXP3 protein

Clone

FXP3/197

Isotype

IgG1, kappa

Symbol

IPEX

GeneID

UniProt ID

Function

Probable transcription factor. Plays a critical role in the control of immune response.

Summary

Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC, IF, FC, IP, E

Images

Specification

Quantity

Related Products

Select Brand Catalog No. Product Name Pack Size Type Field of Research Specification Quantity Price(USD)
1 Leading Biology AMM07977G SPRY1 / Sprouty 1 Antibody (clone 3H4) 50 μg Monoclonal Antibodies
$545.00 Add Ask
2 Leading Biology AMM00137G CD79a (B-Cell Marker) Antibody - With BSA and Azide 50 ug Monoclonal Antibodies
$395.00 Add Ask
3 Leading Biology APG02467G CCK4 / PTK7 Antibody (clone 4F9) 50 μl Monoclonal Antibodies
$495.00 Add Ask
4 Leading Biology AMM05365G DC-SIGN Antibody [5D7] 0.1 mg Monoclonal Antibodies
$695.00 Add Ask
5 Leading Biology AMM01402G Vimentin (Mesenchymal Cell Marker) Antibody - With BSA and Azide 50 ug Monoclonal Antibodies
$395.00 Add Ask
6 Leading Biology APR08280G LTA4H / LTA4 Antibody (clone 9G8) 50 μl Monoclonal Antibodies
$495.00 Add Ask
Contact Us

This item has successfully been added to your cart!

You have 0 item in your cart

Your inquiry has successfully been added to your list!

You have 0 item in your inquiry list