> Antigen, Antibodies, ELISA, Western Blot > Immunoassay Kits > ELISA Kit > Human BMPR2/Bone morphogenetic protein receptor type-2 ELISA KitBrand |
Leading Biology | Catalog Number |
EK00528E |
Product Type |
ELISA Kit | Field of Research |
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Product Overview |
EK00528E is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the A Disintegrin and Metalloprotease 30 (Bone morphogenetic protein receptor type-2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Bone morphogenetic protein receptor type-2 The ELISA analytical biochemical technique of the EK00528E kit is based on Bone morphogenetic protein receptor type-2 antibody-Bone morphogenetic protein receptor type-2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Bone morphogenetic protein receptor type-2 antigen targets in samples. The ELISA Kit is designed to detect native, recombinant, Bone morphogenetic protein receptor type-2. Appropriate sample types may include undiluted human body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV (%).
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Cellular Localization |
Cell membrane Single-pass type I membrane protein
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Assay Type |
Sandwich
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Detection Method |
Spectrophotometrical
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Reactivity |
Human
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Sample Type |
This immunoassay kit allows for the in vitro quantitative determination in Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.
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Sensitivity |
0.082 ng/mL
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Assay Range |
0.156-10 ng/mL
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Kit Components |
Assay Plate, Standard, Sample Diluent, Assay Diluent A&B, Detection Reagent A&B, Wash Buffer, Substrate, Stop Solution.
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Other Reagents Required |
Deionized or distilled water
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Gene Name |
BMPR2
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MIM |
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UniProt ID |
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Function |
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.
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Form |
ELISA Kits |
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Storage & Stability |
Store at +4°C. Please refer to protocols.
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Applications |
FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
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Synonyms |
BMP type-2 receptor,Bone morphogenetic protein receptor type II,BMP type II receptor,PPH1
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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