• Account
  • Account
    Inquiries
    0

    Inquired items

    0 items total Subtotal:$ 0
  • 会员中心
    Cart

    Added items

    0items total Subtotal:$ 0

All Departments

Location: Home > Antigen, Antibodies, ELISA, Western Blot > Engineered Antibodies > Therapeutic Antibodies > Anti-Human SELP Therapeutic Antibody (Crizanlizumab)

Anti-Human SELP Therapeutic Antibody (Crizanlizumab)

Catalog # Availability Size / Price Inquiry
AMH0001R-0.5 mg 0.5 mg / $2950
AMH0001R-1.0 mg 1.0 mg / $3950

Anti-Human SELP Therapeutic Antibody (Crizanlizumab)

Brand

Leading Biology

Catalog Number

AMH0001R

Product Type

Therapeutic Antibodies

Field of Research

Product Overview

Recombinant monoclonal antibody to SELP. Crizanlizumab is a human monoclonal antibody that can be potentially used in the treatment of Sickle Cell Disease (SCD).

Host

CHO

Species Reactivity

Human

Immunogen

The details of the immunogen for this antibody are not available.

Specificity

Human SELP

Conjugation

Unconjugated

Isotype

IgG2, κ

Purification

Affinity purified

GeneID

UniProt ID

Disease

Sickle Cell Disease (SCD)

Purity

> 95% as determined by SDS-PAGE

Storage & Stability

Store at –20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile distilled water or diluent supplied, the antibody is stable for at least two weeks at 2-4 °C.

Applications

Used for immunoassay techniques such as: Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Immunofluorescence; Immunoprecipitation; Flow Cytometry; Functional Studies.

Product Description

This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calciumdependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.

Synonyms

Selectin P; CD62

Images

Specification

Quantity

Related Products

Select Brand Catalog No. Product Name Pack Size Type Field of Research Specification Quantity Price(USD)
Contact Us

This item has successfully been added to your cart!

You have 0 item in your cart

Your inquiry has successfully been added to your list!

You have 0 item in your inquiry list