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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > HFE2 / Hemojuvelin Antibody (clone 1C12)

HFE2 / Hemojuvelin Antibody (clone 1C12)

Catalog # Availability Size / Price Inquiry
AMM05340G 50 μg / $545

HFE2 / Hemojuvelin Antibody (clone 1C12)

Brand

Leading Biology

Catalog Number

AMM05340G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HFE2 / Hemojuvelin antibody (clone 1C12).

Molecular Weight

45kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Lipid-anchor, GPI-anchor

Host

Mouse

Species Reactivity

Human

Target

Human HFE2

Clone

1C12

Symbol

HJV, RGMC

GeneID

UniProt ID

Function

Member of the repulsive guidance molecule (RGM) family. Involved in iron metabolism. Acts as a bone morphogenetic protein (BMP) coreceptor (By similarity). Enhancement of BMP signaling regulates hepcidin (HAMP) expression and iron metabolism (By similarity). May cooperate with hepcidin to restrict iron absorption in the gut. Could represent the cellular receptor for hepcidin.

Summary

Member of the repulsive guidance molecule (RGM) family. Involved in iron metabolism. Acts as a bone morphogenetic protein (BMP) coreceptor (By similarity). Enhancement of BMP signaling regulates hepcidin (HAMP) expression and iron metabolism (By similarity). May cooperate with hepcidin to restrict iron absorption in the gut. Could represent the cellular receptor for hepcidin.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

IHC-P (5 μg/ml)

Synonyms

Hemojuvelin, Hemochromatosis type 2 protein, RGM domain family member C, HFE2, HJV, RGMC

Images

Anti-HFE2 antibody IHC of human small intestine.

Specification

Quantity

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