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PPP2R2B Antibody (clone 1F3)

Catalog # Availability Size / Price Inquiry
APR12943G 50 μg / $545

PPP2R2B Antibody (clone 1F3)

Brand

Leading Biology

Catalog Number

APR12943G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PPP2R2B antibody (clone 1F3).

Molecular Weight

52kDa

Cellular Localization

Antigen Cellular Localization: Isoform 1: Cytoplasm. Cytoplasm, cytoskeleton. Membrane

Host

Mouse

Species Reactivity

Human

Target

Human PPP2R2B

Clone

1F3

GeneID

UniProt ID

Function

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity (By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance (By similarity).

Summary

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity (By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance (By similarity).

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E, IP

Dilution

IHC-P (5 μg/ml)

Synonyms

Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform, PP2A subunit B isoform B55-beta, PP2A subunit B isoform PR55-beta, PP2A subunit B isoform R2-beta, PP2A subunit B isoform beta, PPP2R2B

Images

Immunoprecipitation of PPP2R2B transfected lysate using anti-PPP2R2B monoclonal antibody and...

Specification

Quantity

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