> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > MFGE8 / MFG-E8 Antibody (clone 1E7)Brand |
Leading Biology | Catalog Number |
APR08424G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MFGE8 / MFG-E8 antibody (clone 1E7).
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Molecular Weight |
43kDa
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Peripheral membrane protein Secreted
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Host |
Mouse
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Species Reactivity |
Human
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Target |
Human MFGE8 / MFG-E8
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Clone |
1E7
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GeneID |
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UniProt ID |
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Function |
Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication.
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Summary |
Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E, IP
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Dilution |
IHC-P (5 μg/ml)
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Synonyms |
Lactadherin, Breast epithelial antigen BA46, HMFG, MFGM, Milk fat globule-EGF factor 8, MFG-E8, SED1, Lactadherin short form, Medin, MFGE8
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Images |
Immunoprecipitation of MFGE8 transfected lysate using anti-MFGE8 monoclonal antibody and Protein...
Anti-MFGE8 / MFG-E8 antibody IHC of human lung, epithelium. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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