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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > MFGE8 / MFG-E8 Antibody (clone 1E7)

MFGE8 / MFG-E8 Antibody (clone 1E7)

Catalog # Availability Size / Price Inquiry
APR08424G 50 μg / $545

MFGE8 / MFG-E8 Antibody (clone 1E7)

Brand

Leading Biology

Catalog Number

APR08424G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MFGE8 / MFG-E8 antibody (clone 1E7).

Molecular Weight

43kDa

Cellular Localization

Antigen Cellular Localization: Membrane; Peripheral membrane protein Secreted

Host

Mouse

Species Reactivity

Human

Target

Human MFGE8 / MFG-E8

Clone

1E7

GeneID

UniProt ID

Function

Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication.

Summary

Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E, IP

Dilution

IHC-P (5 μg/ml)

Synonyms

Lactadherin, Breast epithelial antigen BA46, HMFG, MFGM, Milk fat globule-EGF factor 8, MFG-E8, SED1, Lactadherin short form, Medin, MFGE8

Images

Immunoprecipitation of MFGE8 transfected lysate using anti-MFGE8 monoclonal antibody and Protein...

Anti-MFGE8 / MFG-E8 antibody IHC of human lung, epithelium.

Specification

Quantity

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