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MYH9 Antibody (clone 2B3)

Catalog # Availability Size / Price Inquiry
APR17494G 50 μg / $545

MYH9 Antibody (clone 2B3)

Brand

Leading Biology

Catalog Number

APR17494G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MYH9 antibody (clone 2B3).

Molecular Weight

227kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Note=Colocalizes with actin filaments at lamellipodia margins and at the leading edge of migrating cells.

Host

Mouse

Species Reactivity

Human

Target

Human MYH9

Clone

2B3

GeneID

UniProt ID

Function

Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10.

Summary

Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Dilution

IF (10 μg/ml), IHC-P (5 μg/ml),

Synonyms

Myosin-9, Cellular myosin heavy chain, type A, Myosin heavy chain 9, Myosin heavy chain, non-muscle IIa, Non-muscle myosin heavy chain A, NMMHC-A, Non-muscle myosin heavy chain IIa, NMMHC II-a, NMMHC-IIA, MYH9

Images

MYH9 monoclonal antibody, clone 2B3. Western blot of MYH9 expression in human kidney.

Immunofluorescence of monoclonal antibody to MYH9 on HeLa cell. [antibody concentration 10 ug/ml].

Anti-MYH9 antibody IHC of human breast.

Specification

Quantity

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