> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > AKR1C4 / Chlordecone Reductase Antibody (clone 2C11)Brand |
Leading Biology | Catalog Number |
APG01664G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality AKR1C4 / Chlordecone Reductase antibody (clone 2C11).
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Molecular Weight |
37kDa
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm.
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Host |
Mouse
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Species Reactivity |
Human
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Target |
Human AKR1C4
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Clone |
2C11
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Symbol |
CHDR
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GeneID |
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UniProt ID |
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Function |
Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha- androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20- alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
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Summary |
Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha- androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20- alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, E
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Dilution |
IF (15 μg/ml), IHC-P (5 μg/ml),
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Synonyms |
Aldo-keto reductase family 1 member C4, 1.1.1.-, 3-alpha-HSD1, 3-alpha-hydroxysteroid dehydrogenase type I, 1.1.1.357, Chlordecone reductase, CDR, 1.1.1.225, Dihydrodiol dehydrogenase 4, DD-4, DD4, HAKRA, AKR1C4, CHDR
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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