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S100B Antibody

Catalog # Availability Size / Price Inquiry
AMR09798G 100 μl / $545

S100B Antibody

Brand

Leading Biology

Catalog Number

AMR09798G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality S100B antibody.

Molecular Weight

10713 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus

Host

Mouse

Species Reactivity

Human

Clone

9A11B9

Isotype

IgG1

GeneID

UniProt ID

Function

Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, E

Dilution

WB~~1/500 - 1/2000 IHC~~1/500 - 1/2000

Synonyms

Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B, S100B

Images

Figure 1: Western blot analysis using S100B mouse mAb against full-length S100B recombinant protein.

Figure 2: Immunohistochemical analysis of paraffin-embedded human brain, cerebellun using S100B mouse mAb with DAB staining.

Figure 3: Immunohistochemical analysis of paraffin-embedded human brain (A) and human thymus tissues (B), showing cytoplasmic localization using S100B mouse mAb with DAB staining.

Specification

Quantity

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