> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > S100B AntibodyBrand |
Leading Biology | Catalog Number |
AMR09798G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality S100B antibody.
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Molecular Weight |
10713 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Nucleus
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Host |
Mouse
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Species Reactivity |
Human
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Clone |
9A11B9
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Isotype |
IgG1
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GeneID |
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UniProt ID |
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Function |
Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
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Form |
Liquid. In PBS containing 0.02% sodium azide. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC, E
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Dilution |
WB~~1/500 - 1/2000
IHC~~1/500 - 1/2000
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Synonyms |
Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B, S100B
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Images |
Figure 1: Western blot analysis using S100B mouse mAb against full-length S100B recombinant protein.
Figure 2: Immunohistochemical analysis of paraffin-embedded human brain, cerebellun using S100B mouse mAb with DAB staining.
Figure 3: Immunohistochemical analysis of paraffin-embedded human brain (A) and human thymus tissues (B), showing cytoplasmic localization using S100B mouse mAb with DAB staining. |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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