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GATA4 Antibody

Catalog # Availability Size / Price Inquiry
AMM04714G 100 μl / $545

GATA4 Antibody

Brand

Leading Biology

Catalog Number

AMM04714G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GATA4 antibody.

Molecular Weight

46kDa

Cellular Localization

Antigen Cellular Localization: Nucleus

Host

Mouse

Species Reactivity

Human, Rat

Clone

6H10

Isotype

IgG2b

GeneID

UniProt ID

Function

Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1/500 - 1/2000 IHC~~1:200~~1000

Synonyms

Transcription factor GATA-4, GATA-binding factor 4, GATA4

Images

Figure 1: Western blot analysis using GATA4 mouse mAb against rat fetal heart (1) and adult heart (2) tissues lysate.

Figure 2: Immunohistochemical analysis of paraffin-embedded human colon cancer (A), gastric cancer (B) and rectal cancer (C) tissues using FOXA2 mouse mAb with DAB staining.

Specification

Quantity

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