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Fibulin 5 Antibody

Catalog # Availability Size / Price Inquiry
APR11912G 100 μl / $545

Fibulin 5 Antibody

Brand

Leading Biology

Catalog Number

APR11912G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Fibulin 5 antibody.

Molecular Weight

50180 Da

Cellular Localization

Antigen Cellular Localization: Secreted Secreted, extracellular space, extracellular matrix. Note=co-localizes with ELN in elastic fibers.

Host

Mouse

Species Reactivity

Human

Clone

3F10A5; 3F8A12

Isotype

IgG1

Symbol

DANCE

GeneID

UniProt ID

Function

Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (PubMed:18185537). Stabilizes and organizes elastic fibers in the skin, lung and vasculature (By similarity). Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling (PubMed:10428823).

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, E

Dilution

WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000

Synonyms

Fibulin-5, FIBL-5, Developmental arteries and neural crest EGF-like protein, Dance, Urine p50 protein, UP50, FBLN5, DANCE

Images

Figure 1: Western blot analysis using Fibulin5 mouse mAb against truncated fibulin5 recombinant protein (1) and Hela cell lysate (2).

Figure 2: Immunohistochemical analysis of paraffin-embedded human stomach carcinoma (left) and breast carcinoma (right), showing cytoplasmic localization using fibulin5 mouse mAb with DAB staining.

Specification

Quantity

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