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SLC27A5 Antibody

Catalog # Availability Size / Price Inquiry
APR10028G 100 μl / $545

SLC27A5 Antibody

Brand

Leading Biology

Catalog Number

APR10028G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SLC27A5 antibody.

Molecular Weight

75.4kDa

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum membrane; Multi-pass membrane protein

Host

Mouse

Species Reactivity

Human, Mouse

Clone

4B11C10

Isotype

IgG1

Symbol

ACSB, ACSVL6, FACVL3, FATP5

GeneID

UniProt ID

Function

Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, E

Dilution

E~~1/10000 WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000

Synonyms

Bile acyl-CoA synthetase, BACS, 6.2.1.7, Bile acid-CoA ligase, BA-CoA ligase, BAL, Cholate--CoA ligase, Fatty acid transport protein 5, FATP-5, Fatty-acid-coenzyme A ligase, very long-chain 3, Solute carrier family 27 member 5, Very long-chain acyl-CoA synthetase homolog 2, VLCS-H2, VLCSH2, Very long-chain acyl-CoA synthetase-related protein, VLACS-related, VLACSR, SLC27A5, ACSB, ACSVL6, FACVL3, FATP5

Images

Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Figure 1: Western blot analysis using SLC27A5 mAb against human SLC27A5 recombinant protein. (Expected MW is 32.9 kDa)

Figure 2: Western blot analysis using SLC27A5 mAb against HEK293 (1) and SLC27A5 (AA: 508-570)-hIgGFc transfected HEK293 (2) cell lysate.

Specification

Quantity

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